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But you should call your doctor right away if you have: Severe chest pain (could be your heart, not reflux) Trouble swallowing or feeling like food is stuck Throwing up blood or dark material Black, tarry stools Losing weight without trying Heartburn that doesnt improve with medicine Symptoms that last more than 2 weeks Severe belly pain that might reach through to your back Feeling full very quickly and for a long time after small meals If youre experiencing acid reflux and vomiting at the same time, it could be a sign of a more serious condition like gastroparesis (stomach paralysis)

In the case of semaglutide, some healthcare providers have observed changes in seizure patterns among their patients with epilepsy

Many patients also have obesity, insulin resistance, dyslipidemia, fatty liver disease, obstructive sleep apnea, and other conditions that contribute to systemic inflammation and elevated cardiovascular risk