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Description
Mietlicki-Baase EG, Ortinski PI, Reiner DJ, Sinon CG, McCutcheon JE, Pierce RC, et al
market structure generates more complex dynamics
Jura, N., Archer, H
Ethics declarations Financial Support No financial support was received for this research
TM2, in particular, adopts a conformation in the orforglipron-bound structure that would be difficult to predict computationally, highlighting the receptor's conformational flexibility and the inherent limitations of structure-based drug design for class B GPCRs
This variation may be associated with the specificity of the drugs for in receptor interactions
