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2014;8(4):e299-313

Inverse relation of body weight and weight change with mortality and morbidity in patients with type 2 diabetes and cardiovascular co-morbidity: an analysis of the PROactive study population

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When to Seek Advice Contact your GP or diabetes specialist nurse if you experience: Persistent nausea or vomiting that prevents adequate fluid intake (risk of dehydration) Severe, persistent abdominal pain stop taking the medication and seek urgent medical attention as this could indicate pancreatitis Symptoms of hypoglycaemia if taking alongside insulin or sulfonylureas Severe abdominal pain radiating to the back, with or without fever or jaundice (yellowing of skin/eyes) may indicate gallbladder problems Unexplained weight loss or gain outside expected parameters If you're planning pregnancy, discuss with your healthcare provider