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Pax6 is required for differentiation of glucagon-producing alpha-cells in mouse pancreas

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Int J Obes (Lond) 2025;49(3):433451

When catalases (CAT) are deficient, pancreatic islet-cells are more susceptible to excessive formation of reactive oxygen species (ROS) and oxidative stress, which leads to pancreatic islet dysfunction and overt type 2 diabetes mellitus (15)

Despite advances in addiction medicine, FDA-approved pharmacotherapies for SUDs remain limited and have varying efficacy