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GLP-1 impact will appear as small, distributed changes: Slight declines in purchase frequency Shifts in product mix Changes in customer behavior over time These signals require exploratory, multi-dimensional analysis to detect early

In the search for this prophesised molecule, Dr Joel Habener and his team at Massachusetts General Hospital decided in the late 1970s to study glucagon, another hormone produced by the pancreas that has an opposite action to insulin and increases blood glucose levels

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Glucose-dependent insulinotropic peptide secretion is induced by inflammatory stimuli in an interleukin-1-dependent manner in mice

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