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Losing 20 pounds in a month is generally not realistic or healthy

Overall, semaglutide GLP-1 injections offer significant benefits by regulating blood sugar levels, promoting weight loss, and improving overall health outcomes for patients with type 2 diabetes and obesity

Medicina (B Aires)

In multiple sclerosis models, GLP-1 receptor activation reduces pathogenic Th1 and Th17 cell activity, inhibits microglial activation (the brain equivalent of macrophage inflammation), and may enhance remyelination processes

In practice, it seems better to tailor the choice to different patients, depending on the preference of the route of administration (oral vs injectable), the presence of intolerance or side-effects, and contraindications

Most evidence comes from small trials or case reports