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GLP-1 receptor (GLP-1R) agonists, like liraglutide, have shown analgesic effects by modulating pain hypersensitivity in animal models of inflammatory and neuropathic pain

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For example, a large-scale retrospective study using data from the US Department of Veterans Affairs showed GLP-1 use to be associated with a reduced risk of 42 conditions in a diabetic population1

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GLP-1 medications are now accessible at prices below $150 per month through PlexusDx, which offers compounded semaglutide and tirzepatide from licensed 503A pharmacies without insurance requirements