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These GLP-1 analogs affect glucose-dependent insulinotropic polypeptide receptors and glucagon receptors, in addition to GLP-1R and are expected to exhibit stronger anti-obesity effects than that of semaglutide [21, 22]

Overall, the crude analyses generated elevated hazard ratios for all outcomes when we compared GLP-1 receptor agonists with DPP-4 inhibitors
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