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SURMOUNT-5: The First Direct Head-to-Head Trial For years, comparing tirzepatide weight loss results to semaglutide weight loss results required inferring from separate trials run in different patient groups
Tirzepatide does significant heavy lifting on the appetite front, but what you eat still matters
Once side effects stabilize at the new dose (usually within two to four weeks), gradually reintroduce foods as tolerated
Notably, tirzepatide may reduce the effectiveness of oral contraceptives
Severe nausea
