retatrutide type 2 diabetes phase 2 lancet 2023 rosenstock 2: Weight Loss and Key Trial Findings – Bolt Pharmacy Reel by Updates in Medicine

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Used alone or with insulin, they significantly improve after-meal blood sugar levels for most users

Vomiting occurs in about 17% of participants, most commonly during the peak side effect period of weeks 6-8

Severe gastroparesis or significant gastrointestinal motility disorders also warrant avoidance as GLP 1 induced gastric emptying delays can worsen existing symptoms

Conclusions GLP-1 drugs are increasingly popular for their ability to combat obesity, a significant public health problem in the U.S

BMJ 381 , e073312 (2023)