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The UK SmPCs for semaglutide (Wegovy/Ozempic) and tirzepatide (Mounjaro), as well as their EMA European Public Assessment Reports (EPARs), document well-characterised GI side effect profiles that include nausea, vomiting, diarrhoea, constipation, and dyspepsia

Furthermore, patients treated with the dual GLP-1R and GIP agonist tirzepatide exhibited lower Food Craving Inventory scores for sweets and high-fat fast foods compared to those receiving liraglutide, indicating a greater reduction in desire for these items during weight loss (Martin et al., 2025)

When passing through airport security, inform the security officer that you are carrying prescription medication

Ottman N, Davids M, Suarez-Diez M, et al

The gut microbiome itself is changing during GLP-1 treatment through multiple mechanisms, providing biological rationale for considering targeted gut-microbiome support as a parallel layer to the medication

However, it is critical to understand the regulatory landscape