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Unlike Rybelsus, which was the first oral GLP-1 medication but still a peptide, orforglipron is the first non-peptide oral GLP-1 receptor agonist

### Competing Interest Statement ASK, AMM, MCG, JMD, CB, CL, SWB, DJL, PML, DRD, JMC, JPF, YL, ARS, DAT, DWP, SH, RBR, MSL, and DAG are employees and stockholders of Pfizer Inc

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That was when I started using HIMIYER GLP-1 SIX IN-ONE Health Solution Oral Liquid

Promotes GLP-1 activity to naturally enhance fullness, reduce cravings, and improve glycemic response

Retatrutide is now in Phase 3 trials (the TRIUMPH program) for obesity, obesity with Type 2 diabetes, sleep apnea, and knee osteoarthritis