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PubMed , Drug Metabolism and Personalized Therapy , vol

2012 Jun [cited 2019 Jul 19];24(6):5319, e249

Further electrophysiological study showed that, opposite to the effects on arcuate POMC neurons, GLP-1 hyperpolarizes arcuate NPY neurons indirectly via increased GABA A receptor-mediated neurotransmission of local GABAergic interneurons ( Morphological studies demonstrated a particularly high density of GLP-1R expression in the PVN of mice ( Different neural circuits have been proposed to maintain energy homeostasis

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