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Experientia (1986) 42(5):5479

They also said their hair felt stronger, shiner and smoother
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Its not a matter of just adding one mechanism on top of another, but also having to ensure that the single molecule can be equally potent at activating both types of receptors, DiMarchi said

For example, the small-molecule GLP-1 receptor agonist lotiglipron was terminated by Pfizer due to unfavorable hepatic safety signals such as elevated transaminase levels

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