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In addition to directly influencing satiety and appetite control via hypothalamic and hindbrain pathways, GLP-1RAs appear to engage higher-order networks involved in reward processing and emotional regulation, such as the insula, amygdala, and medial prefrontal cortex

The majority of reports of nausea, vomiting, and diarrhea occurred during dose escalation periods in clinical trials

2011;124(1 Suppl):S3S18

doi: 10.1210/jc.2015-3754

These weight loss treatments are gaining attention because they offer more than quick fixes they address how your body manages appetite, energy, and metabolism at a deeper level