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In a significant milestone for type 2 diabetes care, Novo Nordisk has unveiled full results from its SOUL cardiovascular outcomes trial, confirming that oral semaglutide (14 mg) reduces the risk of major adverse cardiovascular events (MACE) by 14 per cent compared to placebo in adults with type 2 diabetes and existing cardiovascular and/or chronic kidney disease.The findings, presented at the American College of Cardiology's (ACC) Annual Scientific Session and Expo in Chicago, and simultaneously published in the New England Journal of Medicine, mark a major advancement in cardiometabolic treatment

Gary Brecka is a Human Biologist, biohacker, researcher, and an anti-aging and longevity expert

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GLP-1GIPlanifibranor, a single-molecule agonist of GLP-1R, GIPR, PPAR, PPAR and PPAR, shows promising therapeutic efficacy against obesity-linked metabolic dysfunction in vitro and in mouse models via synergistic incretin and PPAR activity.