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A scalable, virtual weight management program tailored for adults with type 2 diabetes: effects on glycemic control

In adipocytes, caveolin-1 plays a role in the insulin transduction pathway by modulating the activity of down-stream signaling proteins including Akt (94), raising the possibility that DPP-4 may be able to influence adipocyte insulin sensitivity by modulating the activity of caveolin-1 (Figure 3)

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Clinical studies A total of 22 completed clinical studies were identified (Table 1 and Extended Data Tables 1 and 2), with another 8 clinical trials still ongoing (Supplementary Section 3)