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Conversely, in chronic treated patients the effects on volume changes are slightly reduced because a new steady state is reached, due to a counter-regulatory effect, resulting in a lower total body sodium concentration and blood volume (53)

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In a study of 1.2 million commercially insured U.S

[DOI] [PMC free article] [PubMed] [Google Scholar] 560.Lyssenko V., Lupi R., Marchetti P., Del Guerra S., Orho-Melander M., Almgren P

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If you or your weight management doctor raise concerns about side effects, ask about ways to minimize them, such as starting with a lower dose or adjusting your diet