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Clinical considerations and risk profile Although GLP-1 therapies are highly effective, they are not without risks

They are not a fly-by-night operation that disappears after a few months, but they also lack the established track record of vendors who have been serving the research community for a decade or more

Ageing Res Rev (2021) 72:101464

The base effect: why expected widening amplifies the signal A third of the savings made on food by users of GLP-1 medications are being redirected to other health and wellness categories (clothing, wellness products), according to analysts cited by LinkedIn

Another critical difference: older drugs had minimal metabolic benefits beyond appetite suppression, whereas GLP-1 medications improve insulin sensitivity, reduce inflammation, and show cardiovascular protection independent of weight loss alone

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