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GLP-1 is an incretin hormone that stimulates insulin secretion in a glucose-dependent manner, reducing hypoglycaemia risk The hormone slows gastric emptying and suppresses appetite through receptors in the pancreas, brain, and gastrointestinal tract GLP-1 receptor agonists (semaglutide, liraglutide, dulaglutide) are MHRA-approved for type 2 diabetes and weight management Common side effects include nausea, vomiting, and diarrhoea due to delayed gastric emptying and altered gut motility Patients should seek urgent medical attention for severe abdominal pain with persistent vomiting, as this may indicate pancreatitis GLP-1 medications do not directly impair digestive enzyme production, and routine enzyme supplementation is not clinically indicated Table of Contents What Does GLP-1 Stand For

Understanding what constitutes a normal reaction versus a concerning response helps you manage minor issues confidently while knowing when to seek guidance

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If you're struggling with weight regain or plateaus after bariatric surgery, consult with your doctor about whether Wegovy might be appropriate for your specific situation

However, animal physiology, controlled experimental conditions, and model-specific assumptions can diverge substantially from human biology