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What the Evidence Actually Shows The efficacy signal for semaglutide in weight management is unusually strong for pharmacology, and it is worth being precise about what kind of evidence it is
GLP-1 is vital in reducing food intake (1, 2)
Notably, 92.8% of the weight lost was attributed to fat mass , far exceeding the 71.8% observed with semaglutide monotherapy
Currently, the small molecules category occupies the largest share of the GLP-1 market
DPP-4 is one of the most important classes of drugs in diabetes treatment
Lancet (2009) 374:167786
