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Escalation to specialist or in-person care is warranted if a patient reports symptoms of pancreatitis, significant gastrointestinal side effects, rapid heart rate changes, or signs of dehydration

In a meta-analysis, the I-squared statistic does not tell us how much the effect size varies

The Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus

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Exploring mechanisms to prevent rebound weight gain after discontinuing therapy could also further differentiate products
The treatment for each is completely different, and only a proper assessment can tell you which applies to you
