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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs) were developed as insulinotropic and anti-hyperglycemic agents for the treatment of type 2 diabetes, but their neurotrophic and neuroprotective activities have been receiving increasing attention

This included Matthias Tschp (figure 39), a German who completed a medical degree at Ludwig Maximilian University of Munich in 1993 and then worked as a clinician in neuroendocrinology before taking up a research fellowship at Eli Lilly Discovery Research Laboratories in 1999 to gain expertise in drug discovery and development

[5] GLP-1 upregulation can also directly enhance insulin signaling

Another option is metformin , a drug commonly used for type 2 diabetes that can be combined with GLP-1 analogs to optimize glycemic control and support weight loss

Aim for one to 1.2 grams per kilogram of your ideal body weight