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SGLT2 inhibitors cause a carbohydrate deficit by glucosuria, which leads to an increased glucagon/insulin ratio, the metabolic shift from glucose to lipid utilization causing ketogenesis, and hence euglycemic DKA

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Learn how GLP-1-based therapies like exenatide and liraglutide effectively reduce HbA1c, preserve beta cell function, and promote weight loss in type 2 diabetes.