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2016;129(8):879.e1e6

Diabetes Care 31 , 18161823 (2008)

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Keeping the medication in the main body of the fridge, rather than the door, provides a more consistent temperature

GIP receptor agonism also enhances GLP-1 receptor sensitivity at the hypothalamic level, which is one proposed mechanism for tirzepatide's superior appetite suppression relative to selective GLP-1 agonists

Here is what the 24-week results showed across the main dose groups: 4 mg group lost an average of 7.9% body weight 8 mg group lost an average of 12.9% body weight 12 mg group lost an average of 17.5% body weight Placebo group lost an average of 1.6% body weight Higher doses work faster and produce larger total weight loss