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Thus, further research is crucial to expand effective therapies, particularly those targeting metabolic dysfunction and improving clinical outcomes

Combining the accumulated knowledge on DPP4 will lead to an improved understanding of its impact for health and disease

With weight loss, there is also loss of fat-free mass, which raises concern for the development of sarcopenia

Akuta N, Watanabe C, Kawamura Y et al (2017) Effects of a sodium-glucose cotransporter 2 inhibitor in nonalcoholic fatty liver disease complicated by diabetes mellitus: Preliminary prospective study based on serial liver biopsies

42,43 Several GLP-1R agonists, including exenatide, liraglutide, and semaglutide, have been used in NASH clinical research

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