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The symptoms that occur are likely due to cerebral hypoperfusion secondary to systemic hypotension

Pivotal studies, such as the STEP-HFpEF and SELECT trials, have now expanded their indication to heart failure with preserved ejection fraction (HFpEF) and to non-diabetic populations with obesity and CVD, respectively [11,12]

These are less common but can be more severe: Pancreatitis : Pancreatitis is inflammation of the pancreas

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