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Rotate injection sites with each dose to avoid irritation

This timeline is slightly slower than tirzepatide at equivalent points in the dose escalation, but the endpoint results at maximum tolerated doses are closer than many people expect

For a 5mg dose from a 17mg/mL vial: 5 divided by 17 equals 0.294 mL

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Whilst the funding variation sets a maximum of 12 years, Nice will review the situation again within three years and provide further advice on how the rollout of this medicine can be managed using the learning gained from the initial phase

A consultation will determine if it's the right choice