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Wegovy tablets come in four strengths: 1.5mg, 4mg, 9mg, and 25mg

[9] Semaglutide Efficacy at Low Doses: Slower Progress, Better Comfort Semaglutide (Ozempic/Wegovy) is the most common drug for microdosing, largely because its pen design allows for the click method, a technique I explain step-by-step later in the article

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Muscle loss slows metabolism, reduces strength, and produces a less healthy body composition even at a lower weight

A new side effect for dysesthesia (altered skin sensation) was noted but was mild and rarely led to discontinuation

Patients with established cardiovascular disease (heart attack, stroke history) who benefit from semaglutides proven MACE reduction (SELECT trial) Adolescents aged 1217 with obesity Wegovy is the only approved GLP-1 option in this age group Patients who prefer or need an oral medication option (Rybelsus tablets for type 2 diabetes) Those for whom semaglutide is more affordable or better covered by insurance Patients with metabolic dysfunction-associated steatohepatitis (MASH) Wegovy HD received approval for this indication in 2025 First-time GLP-1 users who want to start with the medication with the longest real-world safety track record Frequently Asked Questions Is tirzepatide stronger than semaglutide