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As the leading cause of female infertility, PCOS is characterized by hyperandrogenism, hormonal imbalances, and metabolic disruptions that impair ovulatory function and menstrual regularity [2]

In addition, preclinical and clinical data were used to study the potential effects of drugs with multiple agonists and pathways through which gut-brain signaling pathways can be used to promote sustained weight loss without side effects

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K., Fink-Jensen, A., Rungby, J., Jrgensen, M

Owing to the promising results, Craft et al

Many patients experience persistent weight gain and insulin resistance even with adequate thyroid hormone replacement, suggesting broader metabolic disruption