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[DOI] [PMC free article] [PubMed] [Google Scholar] 82.Baker L.D., Cross D.J., Minoshima S., Belongia D., Watson G.S., Craft S

This multi-receptor strategy sets it apart from previous generations of weight loss drugs by addressing not just hunger and insulin regulation, but also energy expenditure and fat oxidation

People taking these medicines often say theyre not as hungry and don't think about food as much

National Centralized Drug Procurement and Original Research Drugs All 7 GLP-1RAs are originator drugs, all scored 1 point

The headline findings: - GLP-1 increases nighttime minimum heart rate by ~1.11.2 bpm - HRV drops by ~1.71.8ms and stays down regardless of how much you exercise - Fitter individuals show smaller HR increases, but HRV doesn't budge That last point is the most interesting to me