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Clinical and experimental studies demonstrate that GLP-1RAs decrease hepatic fat content and fibrosis markers, reduce circulating pro-inflammatory cytokines, and promote favorable adipokine profiles, collectively dampening immune activation [9,25]

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doi: 10.1016/j.pupt.2021.102003 [DOI] [PubMed] [Google Scholar] 102

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Cardiometabolic risk factors, such as C-reactive protein, lipids, and blood pressure, were also reduced with semaglutide treatment compared with placebo [49]