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Yes I understand that all clinical trials and any other prospective interventional studies must be registered with an ICMJE-approved registry, such as ClinicalTrials.gov

About one in eight adults (12%) say they have taken one of an increasingly popular class of prescription drugs known as GLP-1s that are used for weight loss and to treat diabetes and reduce the risk of heart disease and stroke, a new KFF Health Tracking Poll finds.

semaglutide, n=21), weight and BMI were 90.5 kg (83.4, 107.9) and 34.0 kg/m2 (31.7, 38.7), respectively, with a post-bariatric weight regain of 15.1% (10.6, 22.8) of total body weight and 4.6 kg/m2 (3.3, 6.2)
ClinicalTrials+1 If these trials succeed, we may see GLP-1 drugs formally approved for brain-health or dementia-prevention in the coming years

Insurers raised cost-sharing sharply for GLP-1s in recent years and also increased use of prior authorization.

A 2024 RCT found semaglutide reduced hip bone density by 2.6% and lumbar spine by 2.1% in one year
