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Germany remains important as a high-spec market for functional nutrition, pharmacy-adjacent wellness, and structured eating formats

Glucagon-like peptide 1-based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study

Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus

Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke

Introduction G protein-coupled receptors are the largest family of membrane proteins targeted by approved drugs ( Obesity is a chronic multifactorial disease ( Glucagon-like peptide-1 receptor (GLP-1R) Processing of the preproglucagon precursor by prohormone convertase 1/3 leads to production of GLP-1, GLP-2, oxyntomodulin, glucagon and glicentin in a tissue-specific manner ( Figure 1 ) ( Figure 1 Oral GLP-1 Although the injectable treatments have reached double digit weight loss, oral therapies are more cost effective and are more likely to achieve long term efficacy through better compliance and combination strategies ( Glucagon receptor (GCGR) GCGR is a family B GPCR activated by glucagon mainly expressed in liver and kidney and, to a lower extent in heart, adipose tissue, pancreas, gastrointestinal tract and other tissues

And the washout period between stopping one and starting the other remains one of the most misunderstood aspects of the entire process