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While long-term clinical studies are ongoing, we can be carefully optimistic that improved GLP-1-based pharmacology can one day be safely applied to further lower body weight relative to currently available GLP-1R agonists

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This is not merely a quantitative difference (more receptor activation)

SGLT-2 inhibitors and cardiovascular risk: an analysis of CVD-REAL

This receptor also helps slow gastric emptying, ultimately reducing whats coming in throughout the day

However, Reddy noted that when given to men who have low testosterone, it may improve their outlook on life, energy, and exercise tolerance