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The maximum dose of Tirzepatide is 15 mg weekly, with titrations often to 5 mg, 10 mg, and then 15 mg, depending on clinical guidelines and individual response

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The remaining trials (TRIUMPH-2/-3/-4 and TRIUMPH-Outcomes) are still anticipated through 20262028

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Whilst mild and transient GI symptoms are common with GLP-1 receptor agonists and are generally not a cause for alarm, certain symptoms warrant prompt medical attention

But a good questions been raised: If youre slowing the gut motility, what impact does that have on the famous ADME of pharmacokinetics