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Clinical testing of these combination therapies will be necessary to determine whether the effects translate to superior weight loss in obese T2DM patients

This raises potential concerns for patients with pancreatic and gastrointestinal neuroendocrine cancer or those with genetic conditions like multiple endocrine neoplasia syndrome (MEN1), which predispose individuals to NENs

While previous generations GLP-1 agonists (liraglutide) have led to weight loss of 5-10% in most cases, semaglutide can lead to weight loss of up to 20%

doi: 10.1210/endo.142.11.8593 51 RothJDHughesHKendallEBaronADAndersonCM

This pain is qualitatively different from common GLP-1 side effects and requires immediate medical evaluation

Ozempic patients nationwide are filing lawsuits against Novo Nordisk, a Danish pharmaceutical company founded in 1923