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Semaglutide significantly improved maximal walking distance in people with symptomatic peripheral arterial disease (PAD) and type 2 diabetes in a trial designed to evaluate the use of a GLP-1 agonist to manage PAD

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Following the initial top-line readout in August which showed a statistically significant, 20% relative risk reduction in MACE-3 cardiovascular events the veil has finally been lifted from the landmark SELECT cardiovascular outcomes trial

The impact of GLP-1 RA on cardiovascular outcomes is unclear
