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Especially at concentrations of 10100 nM Liraglutide lead to a significant reduction in proliferation and DNA synthesis as observed in cell counting, MTS, 3-(4,5-di methylthiazol-2-yl) 2,5-diphenyltetrazolium bromide (MTT) and [H]-thymidine incorporation assays [13, 20]

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Dulaglutide as add-on therapy to SGLT2 inhibitors in patients with inadequately controlled type 2 diabetes (AWARD-10): A 24-week, randomised, double-blind, placebo-controlled trial

doi:10.1056/nejmoa2500969

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They attached a long chain of lipids that can bind to albumin a protein in blood that serves as a carrier for the drugand keep the compound active for hours or even days