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Diabetologia 59:13721375 Liang Y, Osborne MC, Monia BP et al (2004) Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db / db mice

If youre researching weight-loss medications, youve probably seen a lot of discussion around semaglutide and tirzepatide

These include hot flashes, mood swings, vaginal dryness, and weight changes

What youll learn: Fatigue is a possible side effect of tirzepatide, but its relatively uncommon, affecting about 5 to 7% of people

The distribution pattern is distinctive: fat accumulates around the midsection, face, and upper back while limbs may remain relatively thin

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