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Some is from the medication itself

however, the rise was more pronounced for AOM semaglutide

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doi: 10.2337/db21-0459 [DOI] [PMC free article] [PubMed] [Google Scholar] 166.Meier JJ, Goetze O, Anstipp J, et al

This careful escalation exists because gastrointestinal side effects can be significant
