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Feb 1995;25(2):155-61

10 mg Dose: Resulted in an average of 19.5% body weight loss

Protein intake matters more: With enhanced fat oxidation, ensuring adequate protein intake (0.7-1.0 grams per pound of goal body weight) becomes critical for preserving muscle mass

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Assessments Serial assessments of randomly assigned participants are conducted throughout all of the trials and include height, body weight, waist circumference, glucose metabolism (fasting plasma glucose, HbA1c, fasting serum insulin), lipids (total cholesterol, free fatty acids, high-density lipoprotein cholesterol, low-density lipoprotein choles- terol, triglycerides, very-low-density lipoprotein cholesterol), bio- markers (high-sensitivity C-reactive protein, except in the sustained WM trial [STEP 4]), and vital signs (diastolic and systolic blood pressure [millimeters of mercury])

In January 2026, Colorado and Oregons Prescription Drug Affordability Boards (PDABs) advanced key policy and review discussions