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Nutritional priorities for long-term weight maintenance post-therapy Given adherence challenges, clinicians should help individuals establish positive nutrition and other lifestyle practices before and during GLP-1 therapy, to increase success at maintaining such practices if the drug is stopped

Immediate medical attention is necessary if lightheadedness is accompanied by: Chest pain, pressure, or tightness Severe shortness of breath or difficulty breathing Irregular or rapid heartbeat (palpitations) Severe headache, particularly if sudden onset Slurred speech, facial drooping, or weakness on one side of the body Loss of consciousness or fainting episodes Confusion or altered mental status Seizure activity These symptoms may indicate serious cardiovascular or neurological events requiring emergency evaluation

Side effects are usually mild to moderate, and in the clinical trials more than 90% of those treated with semaglutide / Wegovy and tirzepatide / Zepbound were able to stay on the medications

Renal biopsy in patients with diabetes: a pooled meta-analysis of 48 studies

2025, Frontiers in Nutrition

EMD Millipore, Billerica, MA, USA) as described previously (30)