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GLP-1 RA cardiovascular outcome trials in patients with T2D reported a neutral impact of the drugs on HF hospitalisation

PCR showed that Exendin-4 down-regulated the expression of senescence associated gene (p16, p21, p53) and up-regulated the expression of bone-related gene

Glucagon-like peptide 1 (GLP-1) acts as an incretin hormone and anorexigenic neuropeptide, prompting the successful and ongoing development of GLP-1-based therapies for type 2 diabetes and obesity 1,2

In addition to supporting weight management, these medications have shown promising benefits for overall health, including neuroprotection & cardioprotection

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63% of Omada members maintained or kept losing weight 1 year after stopping medication 1 year Omada members largely maintained their weight 1 year after stopping medication FAQs What are GLP-1s