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Large glucose swings, visceral adiposity, fatty liver, and elevated fasting insulin may all signal a metabolic environment that is less favorable for long-term cognitive health

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and that any discrepancies from the study as planned and registered have been explained

(3) outcomes: all clinical outcomes, such as cardiovascular event, death, changing in glycosylated hemoglobin type A1C (HbA1c), body weight, fasting plasma glucose (FPG) and safety outcomes