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Microdosing GLP-1 strategies for stopping semaglutide and tirzepatide treatment and maintaining weight loss

2015;14:73

GI side effects, along with GLP-1 medications impact on appetite, caloric intake, and food choices, can significantly affect nutrition
Current clinical evidence remains limited, making provider consultation essential before starting or continuing these medications while breastfeeding

These results suggest that exendin-4-induced suppression may be mediated by a distinct Gs/cAMP-PKA/IP3/Ca2+/CaM/CaMKII signaling pathway, following the activation of GLP-1Rs.

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