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Once reconstituted, the solution should be refrigerated at 28C and used within approximately 30 days

Leaders across healthcare are emphasizing pairing these medications with lifestyle interventions, especially as emerging data points to kidney and cardiovascular benefits

The authors explicitly suggest reframing switching as part of long-term optimization rather than discontinuation

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Regarding renal effects, the evidence of SGLT2is in preventing kidney failure is more abundant than for GLP-1RAs, which showed a beneficial effect on albuminuria but not on hard kidney endpoints