glp-1 and satiety Frontiers GLP-1R and Diabetes

The researchers found that GLP-1 receptor agonist initiation was associated with a reduced risk for disorders related to alcohol use, cannabis use, cocaine use, nicotine use, opioid use, and other SUDs compared with initiation of SGLT-2 inhibitors (hazard ratios, 0.82, 0.86, 0.80, 0.80, 0.75, and 0.87, respectively) and with a reduced risk for the composite outcome of all incident SUDs (hazard ratio, 0.86)

(24) Preclinical animal models demonstrated that GLP-1 receptor agonists may help protect against fractures and reduce advanced glycation end-product (AGE) accumulation in diabetic subjects

Low protein leads to muscle loss, which lowers metabolic rate, which slows weight loss

GLP-1s can increase insulin production, delay gastric emptying, promote beta-cell proliferation, and decrease appetite

Most Weight Loss Drugs Aren't Approved for Weight Loss In fact, most drugs being used for weight loss weren't even intended for that purpose

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