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Description
Called liraglutide, the company began clinical testing of the drug for diabetes in 1997
GLP-1/glucagon receptor co-agonism for treatment of obesity
In the medulla, GLP-1R was observed in the area postrema, NTS, and lateral reticular nucleus [393]
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Insulin has also been suggested to play a significant role as a paracrine regulator of glucagon secretion (the intra-islet hypothesis), although the mechanism by which this inhibition occurs is not well elucidated (133)
Both target GLP-1 receptors
