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That second hormone, GIP, matters significantly more than anyone realized

95% CI, 2.91-3.61) than those using semaglutide

In SURMOUNT-1 (72 weeks), tirzepatide produced mean reductions of 15%, 19.5% and 20.9% at the 5, 10 and 15 mg doses versus 3.1% on placebo, and 90.9% of the 15 mg group lost at least 5% of starting weight
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